The most effective and engaging way for clinicians to learn, improve their practice, and prepare for board exams. NEW! Peer-reviewed journal featuring in-depth articles to accelerate the transformation of health care delivery.Ĭoncise summaries and expert physician commentary that busy clinicians need to enhance patient care. The Masimo Foundation does not provide editorial input.NEW! A digital journal for innovative original research and fresh, bold ideas in clinical trial design and clinical decision-making. “We want to have evidence and answer these questions with the best possible design and rigor that’s necessary for people to make informed decisions.”įollow Adrianna Rodriguez on Twitter: and patient safety coverage at USA TODAY is made possible in part by a grant from the Masimo Foundation for Ethics, Innovation and Competition in Healthcare. “The higher dose and longer duration hasn’t been studied and that has been some of the critiques" from ivermectin proponents, Hernandez said. They’re currently studying a higher dose of 600 micrograms for a longer duration, six days instead of three. Pierre Kory, president and chief medical officer of the FLCCC, argued the new findings showed ivermectin had a "modest impact" on COVID-19 recovery, adding to "existing evidence of efficacy."īut evidence cited by the organization are mostly observational studies that health experts say were poorly designed, relied on subjective measures for success and left room for bias. They also appeared in lesser-known journals that lack rigorous peer-review.ĭespite the mounting evidence against ivermectin, Hernandez said his team would continue to research the medication and its effect on COVID-19 recovery and hospitalization. Many of the doctors who prescribe ivermectin follow treatment guidelines set by an organization called the Front Line COVID-19 Critical Care Alliance, which promotes the controversial drug, along with other unproven therapies.ĭr. The company also reported fills spiking in August, December and January, correlating with the delta and omicron waves, respectively. SingleCare, a free prescription savings service, reported a 90% increase in ivermectin prescriptions filled from January to June when compared with the same time last year. "It’s frustrating that people continue to prescribe it and direct people away from proven therapies . Amesh Adalja, a senior scholar at the Johns Hopkins Center for Health Security, said in February. “Most of us have really repudiated its use for COVID-19," Dr. Hundreds of doctors continue to prescribe the drug to treat COVID-19 patients despite warnings from health experts.
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Patients given ivermectin recovered in about 11 days on average, while patients given the placebo recovered in about 11.5 days.
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In the eight-month study conducted during the delta and omicron waves, authors found no statistical difference in recovery time. Adrian Hernandez, executive director of the Duke Clinical Research Institute, said vaccinated participants were evenly distributed in both groups. Researchers from Duke University and Vanderbilt University recruited 1,537 participants, with about half of them receiving 400 micrograms of ivermectin for three days and the other half a placebo to see how long it took them to recover from COVID-19.įorty-seven percent of the volunteers reported receiving at least two doses of COVID-19 vaccine. The randomized, double-blind, placebo-controlled trial – the gold standard for determining effectiveness of drugs – is the largest of its kind studying the controversial antiparasitic. Preliminary results from a trial funded by the National Institutes of Health adds to a mountain of evidence showing ivermectin is not effective at treating COVID-19.